Assessment of temporal functional changes and miRNA profiling of human iPSC-derived cardiomyocytes

Kumar N, Dougherty JA, Manring HR, Elmadbouh I, Mergaye M, Czirok A, Greta Isai D, Belevych AE, Yu L, Janssen PML, Fadda P, Gyorke S, Ackermann MA, Angelos MG, Khan M.

Sci Rep, 2019

Summary:

In this study, hiPSC-CM's were evaluated in a label-free MEA array and found to show improved functional, maturation, which has important implications for drug screening and cell transplant studies.

DIn this study, hiPSC-CM's were evaluated in a label-free MEA array and found to show improved functional, maturation, which has important implications for drug screening and cell transplant studies.

Keywords: cardiac development, maturation, characterization, fatty acid oxidation