Changes in neuronal activity in rat primary cortical cultures induced by illicit drugs and new psychoactive substances (NPS) following prolonged exposure and washout to mimic human exposure scenarios

Zwartsen A, Hondebrink L, Westerink RH.

Neurotoxicology, 2019

Summary:

See how Maestro MEA technology makes it possible to use rat primary cortical cultures to study the effect of new psychoactive substances (NPS) on neuronal activity. 

Keywords: new psychoactive substance, addiction, drug abuse, neurotoxicology, stimulants, amphetamine, cathinones, hallucinogen, cocaine, piperazine, reversibility, neuronal network