Phillips AW, Nestor JE, Nestor MW.
Jove, 2017
Summary:
Explore how Maestro MEA technology helped to create a 3-D model that can be used like an organotypic slice culture to model human cortical development and for the physiological interrogation of developing neural circuits.
Keywords: serum-free, maturation, embryoid body, organoid, spheroid, minibrain, network activity, network development
Developing hiPSC Derived Serum Free Embryoid Bodies for the Interrogation of 3-D Stem Cell Cultures Using Physiologically Relevant Assays