Huo J, Wei F, Cai C, Lyn-Cook B, Pang L.
Toxicol Sci, 2018
This study evaluated the sex-differences in drug-induced QT prolongation in human induced pluripotent stem cell cardiomyocytes (hiPSC-CMs) and found that females may be more susceptible to proarrythmias due to differential expression in KCNE1 gene resulting in reduced replorarization reserve.