Rajamani U, Gross AR, Hjelm BE, Sequeira A, Vawter MP, Tang J, Gangalapudi V, Wang Y, Andres AM, Gottlieb RA, Sareen D.
Cell Stem Cell, 2018
Summary:
Discover how Maestro technology helped researchers use differentiated hypothalamic-like neurons (iHTNs) derived from normal and obese patients to show how these cells provide a powerful platform to study obesity and gene-environment interactions.
Keywords: obesity, ghrelin, leptin, hypothalamic neuron, neuropeptides, axonal guidance, glutamate receptors, endoplasmic reticulum, gene-environment interaction, transcriptomic