Freudenrich T, Wallace K, Haag D, Saavedra L, Mall M, Mundy WR, Davila J, Südhof TC, Wernig M, Shafer TJ
Safety Pharmacology Society, 2020
Summary:
Neucyte presents a novel iPSC-derived neuronal/glial in vitro assay for quantifying neurological liabilities of chemical compounds. Defined ratios of glutamatergtic neurons, GABAergic neurons, and astroglial cells on multielectrode arrays produced robust synchronized network activity capable of predicting neurotoxic liability of 6 reference compounds.
* This poster is shared by Neucyte