OXR1 Regulates Cellular Senescence and Neuronal Aging Through Retromer-Mediated Actin Branching

Authors: Kenneth A Wilson, Tyne LM McHugh, Sydney Alderfer, Anna L Girtle, Cristian Geronimo-Olvera, Harrison Baker, Anshuman Das, Jacob Rose, Jordan Burton, Carlos Galicia Aguirre, Elena Battistoni, Mikayla Hady, Catherine Cai, Indra Heckenbach, Alexandra Afenjar, Philippe M Campeau, Peter L Oliver, Akos A Gerencser, Pankaj Kapahi, Birgit Schilling, and Lisa M Ellerby

The Buck Institute for Research on Aging, Novato, California, USA; University of Southern California, Los Angeles, California, USA; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark; Hôpital Armand Trousseau, Groupe Hospitalier Universitaire Paris, France; CHU Sainte-Justine, Montreal, Canada; MRC Harwell Institute, Didcot, United Kingdom.

Presented by Kenneth A Wilson at Cold Spring Harbor Laboratory Symposium: Senescence & Aging 2025