Assessment of spontaneous neuronal activity in vitro using multi-well multi-electrode arrays: Implications for assay development

Negri J, Menon V, Young-Pearse TL.

eNeuro, 2020

Summary:

In this publication, Negri et al. propose Maestro MEA data acquisition and analysis best practices using recordings from primary rat cortical cultures. Additionally, spike sorting was implemented to assess the dynamic firing frequency across populations.

Keywords: spike sorting, assay optimization