Cold-Inducible RNA-Binding Protein Prevents an Excessive Heart Rate Response to Stress by Targeting Phosphodiesterase

Xie D, Geng L, Xiong K, Zhao T, Wang S, Xue J, Wang C, Wang G, Feng Z, Zhou H, Li Y, Li L, Liu Y, Xue Z, Yang J, Ma H5, Liang D, Chen YH.

Circulation Research, 2020

Summary:

Learn how Maestro MEA was used to clarify the role of CIRP in sinus node plasticity and heart rate regulation under stress conditions.

Keywords: Calcium signaling, Pacemaker activity, hiPSC-CMs, Cardiomyocytes