A cross-correction gene therapy approach for CDKL5 deficiency disorder improves the pathological phenotype of CDD patient-derived cortical organoids

Authors: Giorgio Medici, Angelica M. Bove, Stefania Trazzi, Francesca Puppo, Manuela Loi, Nicola Mottolese, Giulia Candini, Federica Trebbi, Sandra Sanchez, Alysson R. Muotri, and Elisabetta Ciani

Frontiers in Bioengineering and Biotechnology, 20 January 2026