Authors: Pamies D, Barreras P, Block K, Makri G, Kumar A, Wiersma D, Smirnova L, Zhang C, Bressler J, Christian KM, Harris G, Ming GL, Berlinicke CJ, Kyro K, Song H, Pardo CA, Hartung T, Hogberg HT.
ALTEX, 2016
Summary:
Discover how Maestro technology helped researchers develop a reproducible iPSC-derived human 3-D brain microphysiological system (BMPS) in order to investigate neuron-neuroglia function in neurotoxicology and other pathogenic mechanisms.
Keywords: brain organoid, spheroid, myelination, neural characterization and development, glia, maturation, oligodendroglia, multiple sclerosis, demyelination, neuroglia, neurotoxicology
A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity
