Wainger BJ, Kiskinis E, Mellin C, Wiskow O, Han SS, Sandoe J, Perez NP, Williams LA, Lee S, Boulting G, Berry JD, Brown RH Jr, Cudkowicz ME, Bean BP, Eggan K, Woolf CJ.
Cell Reports, 2014
iPSC-derived motor neurons with SOD1 mutations are used to study a hyperexcitability phenotype observed in clinical neurophysiological studies.
Keywords: ALS, amyotrophic lateral sclerosis, neurodegeneration, motor neuron, SOD1, Kv7
Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons
