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The Alzheimer’s gene SORL1 is a regulator of endosomal traffic and recycling in human neurons
Author: Mishra S, Knupp A, Szabo MP, Williams CA, Kinoshita C, Hailey DW, Wang Y, Andersen OM, and Young JE.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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[PRE-PRINT] SARS-CoV-2 Viral Genes Compromise Survival and Functions of Human Pluripotent Stem Cell-derived Cardiomyocytes via Reducing Cellular ATP Level
Author: Liu J, Zhang Y, Wu S, Han L, Wang C, Liu S, Simpson E, Liu Y, Wang Y, Shou W, Liu Y, Rubart-von der Lohe M, Wan J, and Yang L.
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[PRE-PRINT] Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality.
Author: Sabate-Soler S, Nickels SL, Saraiva C, Berger E, Dubonyte U, Barmpa K, Lan YJ, Kouno T, Jarazo J, Robertson G, Sharif J, Koseki H, Thome C, Shin JW, Cowley SA, and Schwamborn JC.
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In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas
Author: Ottavi S, Scarry SM, Mosior J, Ling Y, Roberts J, Singh A, Zhang D, Goullieux L, Roubert C, Bacqué E, Lagiakos HR, Vendome J, Moraca F, Li K, Perkowski AJ, Ramesh R, Bowler MM, Tracy W, Feher VA, Sacchettini JC, Gold BS, Nathan CF, and Aubé J.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Optimization of Long-Term Human iPSC-Derived Spinal Motor Neuron Culture Using a Dendritic Polyglycerol Amine-Based Substrate
Author: Thiry L, Clément JP, Haag R, Kennedy TE, and Stifani S.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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[PREPRINT] Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues
Author: Limone F, Mitchell JM, San Juan IG, Smith JLM, Raghunathan K, Couto A, Ghosh SD, Meyer D, Mello CJ, Nemesh J, Smith BM, McCarroll S, Pietiläinen O, Nehme R, and Eggan K.
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[PREPRINT] Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Author: Unda BK, Chalil L, Yoon S, Kilpatrick S, Xing S, Murtaza N, Cheng A, Afonso A, McCready E, Ronen G, Howe J, Caye-Eude A, Verloes A, Doble BW, Faivre L, Vitobello A, Scherer SW, Lu Y, Penzes P, and Singh KK.
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Thyroid hormones regulate cardiac repolarization and QT-interval related gene expression in hiPSC cardiomyocytes
Author: Ulivieri A, Lavra L, Magi F, Morgante A, Calò L, Polisca P, Salehi LB, and Sciacchitano S.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction
Author: Ezerskiy LA, Schoch KM, Sato C, Beltcheva M, Horie K, Rigo F, Martynowicz R, Karch CM, Bateman RJ, and Miller TM.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Edaravone activates the GDNF/RET neurotrophic signaling pathway and protects mRNA-induced motor neurons from iPS cells
Author: Li Q, Feng Y, Xue Y, Zhan X, Fu Y, Gui G, Zhou W, Richard JP, Taga A, Li P, Mao X, Maragakis NJ, Ying M.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,