Publication

hERG deficient human embryonic stem cell with cardiomyocyte and AT prolongation
Publication
hERG-Deficient Human Embryonic Stem Cell-Derived Cardiomyocytes for Modelling QT Prolongation
Author: Chang Y, Li Y-N, Bai R, Wu F, Ma S, Saleem A, Zhang S, Jiang Y, Dong T, Guo T, Hang C, Lu W-J, Jiang H, Lan F.
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
2020 publication on ALS and motor neuron disease
Publication
The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease
Author: Bakkar N, Starra A, Rabichowa BE, Lorenzini I, McEachin ZT, Kraft R, Chaung M, Macklin-Isquierdo M, Wingfield T, Carhart B, Zahler N, ChangW-H, Bassell GJ, Betourne A, Boulis N, Alworth SV, Ichida JK, August PR, Zarnescu DC, Sattler R, Bowser R.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
SOT 2021 hippocampal neuronal networks
Publication
Structure-Activity Relationship of Neuroactive Steroids, Midazolam, and Perampanel towards Mitigating Tetramine-Triggered Activity in Murine Hippocampal Neuronal Networks
Author: Antrobus S, Pressly B, Nik AM, Wulff H, Pessah IN.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2021 Nature Molecular Psychiatry bipolar disorder publication
Publication
Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients
Author: Santos R, Linker SB, Stern S, Mendes APD, Shokhirev MN, Erikson G, Randolph-Moore L, Racha V, Kim Y, Kelsoe JR, Bang AG, Alda M, Marchetto MC, Gage FH.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 EMBO Muotri Neural organoids and MEA paper
Publication
Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids
Author: Trujillo CA, Adams JW, Negraes PD, Carromeu C, Tejwani L, Acab A, Tsuda B, Thomas CA, Sodhi N, Fichter KM, Romero S, Zanella F, Sejnowski TJ, Ulrich H, Muotri AR.
Product: Maestro Pro, CytoView MEA Plate, Neural Module,
2020 Publication JACC LEAP and proarrhythmic risks in hiPSC-CMs
Publication
Rapid Assessment of Proarrhythmic Potential Using Human iPSC-Derived Cardiomyocytes
Author: Geiger RM, Klein MG, Fatima N, Goldstein RE, Krantz MJ, Haigney MC, Flagg TP.
Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,
2020 Neuron Wang Publication on therapeutics for Alzheimers Disease
Publication
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
Author: Wang M, Li A, Sekiya M, Beckmann ND, Quan X, Schrode N, Fernando MB, Yu A, Zhu L, Cao J, Lyu L, Horgusluoglu E, Wang Q, Guo L, Wang, Y-S, Neff R, Song W-M, Wang E, Shen Q, Zhou X, Ming C, Ho S-M, Vatansever S, Kaniskan HU, Jin J, Zhou M-M, Ando K, Ho L, Slesinger PA, Yue Z, Zhu J, Katsel P, Gandy S, Ehrlich ME, Fossati V, Noggle S, Cai D, Haroutunian V, Iijima KM, Schadt E, Brennand KJ, Zhang B.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Plos Biology Bauer
Publication
Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C
Author: Bauer L, Manganaro R, Zonsics B, Hurdiss DL, Zwaagstra M, Donselaar T, Welter NGE, van Kleef RGDM, Lopez ML, Bevilacqua F, Raman T, Ferla S, Bassetto M, Neyts J, Strating JRPM, Westerink RHS, Brancale A, van Kuppeveld FJM.
Product: Maestro Pro, Neural Module, BioCircuit MEA Plate,
2020 mechanisms of QT prolongation on MEA system
Publication
Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block
Author: Tran PN, Sheng J, Randolph AL, Baron CA, Thiebaud N, Ren M, Wu M, Johannesen L, Volpe DA, Patel D, Blinova K, Strauss DG and Wu WW.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
2020 publication neuronal medium optimized for optogenetics
Publication
BrainPhys neuronal medium optimized for imaging and optogenetics in vitro
Author: Zabolocki M, McCormack K, van den Hurk M, Milky B, Shoubridge AP, Adams R, Jenne Tran J, Mahadevan-Jansen A, Reineck P, Thomas J, Hutchinson MR, Mak CKH, Añonuevo A, Chew LH, Hirst AJ, Lee VM, Knock E and Bardy C.
Product: Maestro Pro, Neural Module, Lumos MEA Plate, Lumos,