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ISSCR 2021 Innovation showcase video
Video
ISSCR 2021: Neural activity in a dish: Advancing our understanding of nervous system disorders
Evangelos Kiskinis, Ph.D. and David Belair, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Culture of Rat Primary Cortical Cells for Microelectrode Array (MEA) Recordings to Screen for Acute and Developmental Neurotoxicity
Author: Gerber L-S, van Melis LVJ, van Kleef RGDM, de Groot A, and Westerink RHS.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2021_CellPress_Li_usingthedcas9-krabsystem.png
Publication
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
Author: Li A, Cartwright S, Yu A, Ho Seok-Man, Schrode N, Deans PJM, Matos MR, Garcia MF, Townsley KG, Zhang B, and Brennand KJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2021 publication nature using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion
Publication
Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome
Author: Chapman G, Alsaqati M, Lunn S, Singh T, Linden SF, Linden DEJ, van den Bree MBM, Ziller M, Owen MJ, Hall J, Harwood AJ and Syed YA.
Product: Maestro Pro, CytoView MEA Plate, Neural Module,
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News
Measuring Real-Time Cell Therapy Potency With Bioelectronic Assays
Author: Jim Ross, PhD
Product: Maestro Pro, Maestro Z, Impedance Module, Maestro Edge, Maestro ZHT, GxP Impedance Module,
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Publication
Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation
Author: Huang X, Roet KCD, Zhang L, Brault A, Berg AP, Jefferson AB, Klug-McLeod J, Leach KL, Vincent F, Yang H, Coyle AJ, Jones LH, Frost D, Wiskow O, Chen K, Maeda R, Grantham A, Dornon MK, Klim JR, Siekmann MT, Zhao D, Lee S, Eggan K, and Woolf CJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
ISSCR 2021 poster - Axion BioSystems
Poster
Characterization of an in vitro synaptic propagation assay using iPSC-derived neurons and multiwell MEA technology
Author: Daniel Millard, Denise Sullivan, Heather Hayes
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
[PRE-PRINT] Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies
Author: Fenix AM, Miyaoka Y, Bertero A, Blue S, Spindler MJ, Tan KKB, Perez-Bermejo J, Chan AH, Mayer SJ, Nguyen T, Russell CR, Lizarraga P, Truong A, So P-L, Kulkarni A, Chetal K, Sathe S, Sniadecki NJ, Yeo GW, Murry CE, Conklin BR, and Salomonis N.
Product:
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Publication
A peptide encoded within a 5′ untranslated region promotes pain sensitization in mice
Author: Barragan-Iglesias P, Kunder N, Wanghzou A, Black B, Ray PR, Lou TF, Bryan de la Peña J, Atmaramani R, Shukla T, Pancrazio JJ, Price TJ, and Campbell ZT.
Product:
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Publication
Two independent mouse lines carrying the Nav1.7 I228M gain-of-function variant display dorsal root ganglion neuron hyperexcitability but a minimal pain phenotype
Author: Chen L, Wimalasena NK, Shim J, Han C, Lee SI, Gonzalez-Cano R, Estacion M, Faber CG, Lauria G, Dib-Hajj SD, Woolf CJ, and Waxman SG.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Bioelectronic assays video
Video
Bioelectronic assays - the future of biomedical research
Axion BioSystems
Product: Maestro Pro, Maestro ZHT, Neural Module, Cardiac Module, Impedance Module, CytoView MEA Plate, CytoView-Z Plate,
CiPA publication on hiPSC-cardiomyoctytes
Publication
Development and validation of dual-cardiotoxicity evaluation method based on analysis of field potential and contractile force of human iPSC-derived cardiomyocytes / multielectrode assay platform
Author: Lee S-G, Kim J, Oh M-S, Ryu B, Kang K-R, Baek J, Lee J-M, Choi S-O, Kim C-Y and Chung HM.
Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,
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News
Monitoring the Potency of Cell Therapies Using Bioelectronic Assays
Author: Jim Ross
Product: Maestro Z, Impedance Module, CytoView-Z Plate, Maestro ZHT, GxP Impedance Module,
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Publication
Sex-Specific Cannabidiol- and Iloperidone-Induced Neuronal Activity Changes in an In Vitro MAM Model System of Schizophrenia
Author: Thériault RK, St-Denis M, Hewitt T, Khokhar JY, Lalonde J, and Perreault ML.
Product:
Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies
Publication
Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies
Author: Shih P-Y, Kreir M, Kumar D, Seibt F, Pestana F, Schmid B, Holst B, Clausen C, Steeg R, Fischer B, Pita-Almenar J, Ebneth A, and Cabrera-Socorro A.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
384-well adherent cell plating protocol
Culture Protocol
Adherent Cell Lines on 384-well plate protocol
Author: Axion BioSystems
Product: Maestro ZHT, Impedance Module, CytoView-Z Plate, Impedance Automation Module,
Adherent Cell Culture Protocol
Culture Protocol
Adherent Cell Lines Protocol
Author: Axion BioSystems
Product: Maestro ZHT, Impedance Module, CytoView-Z Plate, Maestro Z, Impedance Automation Module,
Non-adherent cell culture protocol on Axion Maestro system
Culture Protocol
Non-Adherent Cell Lines Protocol
Author: Axion BioSystems
Product: Maestro ZHT, CytoView-Z Plate, Impedance Module, Maestro Z, Impedance Automation Module,
16p211.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro
Publication
16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro
Author: Sundberg M, Pinson H, Smith RS, Winden KD, Venugopal P, Tai DJC, Gusella JF, Talkowski ME, Walsh CA, Tegmark M and Sahin M.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
MEA assay with hiPSC-neurons
Poster
MEA assay with human iPSC-derived neurons generated by a rapid differentiation method
Author: Elixirgen Scientific
Product: Maestro Pro, Neural Module, CytoView MEA Plate,