Ishikawa M, Aoyama T, Shibata S, Sone T, Miyoshi H, Watanabe H, Nakamura M, Morota S, Uchino H, Yoo AS, Okano H.
Cells, 2020
Summary:
miRNAs are used as reprogramming effectors to directly differentiate fibroblasts to neurons and then applied to iPSCs from Alzheimer's patients.
Keywords: microRNA, neurogenin2, presenilin1, presenilin2, Alzheimer's disease, AD, amyloid beta